Api

A migration guide that helps update codebases using older Claude models (Sonnet 4.0, Sonnet 4.5, Opus 4.1) to Claude Opus 4.5. It provides model string mappings across platforms (Anthropic API, AWS Bedrock, Vertex AI, Azure), effort parameter configuration, and prompt adjustment snippets for handling Opus 4.5's behavioral differences like tool overtriggering and over-engineering tendencies.

Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.

Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.

Query ChEMBL's bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.