Structural Biology

This skill enables access to the RCSB Protein Data Bank, the worldwide repository for 3D structural data of biological macromolecules. It supports searching for protein and nucleic acid structures by text, sequence, or structural similarity, downloading coordinate files in various formats, and retrieving metadata for structural biology and drug discovery workflows.

This skill enables access to the AlphaFold Protein Structure Database, providing code examples and documentation for retrieving AI-predicted 3D protein structures. It supports querying by UniProt ID, downloading coordinate files (PDB/mmCIF), analyzing confidence metrics (pLDDT, PAE), and bulk data access via Google Cloud for structural biology and drug discovery workflows.

Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.